Dr. Thokhir Basha Shaik

11+ years in data analytics, bioinformatics, and biotechnology. Expert in dashboards, ML prototypes, and cheminformatics for Pharma, Biotech, and Environmental Health.

Skills

Data Analysis & Visualization

SQL (PostgreSQL), Power BI (DAX, Power Query), Python (Pandas, scikit-learn), R (tidyverse, ggplot2), PCA, ANOVA, regression.

Bio/Cheminformatics

Docking (AutoDock, SwissDock), ADMET, QSAR, BLAST, FASTA, PyMOL, ChimeraX, SwissADME, NCBI, UniProt, PDB.

Machine Learning & R&D

Regression, ANN, Random Forest, Experimental Design, QC Protocols, SOP Development.

Projects

Water Quality Dashboard (Pre vs Post-Monsoon)

Excel dashboard across 8 stations with pies, bars, and rankings for DWQI, IWQI, AWQI, LWQI. Identified tail-end deterioration pre-monsoon and dilution post-monsoon.

Statistical Analysis of Water Quality Data

Analyzed seasonal variations, rejected null hypothesis, visualized with bell curves for DWQI, IWQI, AWQI, LWQI.

Empirical vs ideal bell curves for water quality indices

Chennai Reservoir Water Levels (2005–2019)

Power BI dashboard with filters, showing peak in 2011 and decline by 2019 across four reservoirs.

Health and Wellness Trends Across Age Groups

Analyzed lifestyle data for stress, sleep, heart rate, and activity across age groups 18-90.

AI vs Reality: Herbicide Analysis

Compared AI tools (Grok, ChatGPT, Gemini) with SwissADME for herbicide properties.

Comparison of AI outputs with SwissADME

AI Herbicide Design - Part 1

Designed AI-based herbicides, analyzed descriptors and toxicity using Power BI.

AI Herbicide Design - Part 2

Compared binding energies of AI-designed herbicides using SwissDock and Python.

Docking results of AI-designed herbicides

Experience

Research Associate - SRKR Engineering College

Nov 2020 - Present, India

  • Commissioned analytical instruments (HPLC, Spectrophotometer) per EU standards.
  • Trained teams in APHA sampling and analysis.
  • Built Power BI dashboards and led ML model selection for water quality.
  • Developed Social Vulnerability Index (SVI) methodology in Python.

Junior Research Scientist - Eesavyasa Technologies Pvt. Ltd.

Nov 2017 - Apr 2019, Hyderabad, India

  • Developed 6 rapid water testing kits with SOPs.
  • Prototyped devices like room fumigator and ozone-based vegetable washer.

Project Assistant II & Researcher - CSIR-IICT

Dec 2006 - Sep 2016, Hyderabad, India

  • Collaborated with King’s College London on cancer drug screening.
  • Patented bioprocess for acrylic acid conversion.
  • Conducted target-based screening and mechanistic assays.

Services

Data Analysis & Dashboards

Interactive Power BI reports, ETL workflows, and KPI design.

Machine Learning

Feature engineering and model selection for classification/regression.

Bio/Cheminformatics

Docking, ADMET/QSAR, descriptor pipelines, visual summaries.

R&D Support

Process optimization, experimental design, clean SOPs.

Education

Ph.D., Biotechnology

CSIR-IICT & Acharya Nagarjuna University - 2019, Hyderabad, India

Drug Delivery Exchange

King’s College London - 2013, UK

M.Sc. Biotechnology (84.7%)

Bharathidasan University - 2006, Tiruchirapalli, India

B.Sc. Microbiology, Biochem, Chem (75.3%)

Nagarjuna University - 2002, Guntur, India

Innovative Works & Products

Social Vulnerability Index (SVI) Model

Developed a Python-based SVI model integrating physico-chemical and biological water quality data for environmental policy.

AI-Driven Herbicide Design

Innovated AI-based herbicide molecules with enhanced binding and toxicity profiles using SwissDock and Python.

Microemulsion Delivery System

Designed a 5-fold more effective microemulsion for anticancer drug delivery during Ph.D. research.

Room & Apron Fumigator Prototypes

Prototyped a room fumigator using scrap and developed a wearable apron fumigation device for sterilization.

Ozone-Based Vegetable Washer Prototype

Created a prototype to remove pesticides and fertilizers from vegetables.

Rapid Water Testing Kits

Developed and validated 6 kits for detecting pathogenic bacteria in drinking water, with manufacturing-ready SOPs.

Microbial Bioconversion Process

Patented process for converting acrylonitrile to acrylic acid using HPLC-validated methods.

Contact

Open to roles and freelance engagements. Share a brief, and I’ll respond quickly.